Triple negative breast cancer tumors that lack retinoblastoma protein (pRb) are much more likely to react positively to chemotherapy than TNBC tumors with pRb. Researchers studied 53 TNBC patients; at a follow-up of 105 months (8.75 years), all were disease-free after standard chemotherapy regimens. The research was published in the Annals of Oncology in June 2009 and was conducted in Bologna, Italy.

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